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  • Dr Roya Rozati Delivers An Insightful Talk on Latest Advancements in Preimplanatation Genetic Testing

    Dr. Roya Rozati, a leading expert in reproductive medicine, delivered an insightful talk on Preimplantation Genetic Testing (PGT) as part of IVF treatment during the 2nd International Conference titled MicroemBART 2.0 at the Park Hotel in Hyderabad. The focus was the theme Fertilization Secret Unveiled.

    Her talk simplified complex genetic concepts, highlighted the role of PGT in improving IVF success rates, and emphasized how it helps ensure healthier pregnancies.

    A must-know topic for anyone exploring fertility options!

    Stay tuned for highlights from the session.

  • Understanding Preimplantation Genetic Testing (PGT) in IVF – A Simple Guide

    When couples go through IVF (In Vitro Fertilization), they’re often hoping for the best possible chance at a healthy pregnancy. One of the medical tools that can help improve those chances is Preimplantation Genetic Testing (PGT). If the term sounds complicated, don’t worry — this blog will break it down in a simple, clear way.

    What is Preimplantation Genetic Testing (PGT)?

    Preimplantation Genetic Testing is a technique used during IVF to check the embryos for genetic problems before they are placed in the uterus.

    Think of it as a health check-up for embryos. Scientists take a few cells from each embryo and look at their genetic makeup. This helps doctors choose the healthiest embryos to transfer — ones that are more likely to lead to a successful pregnancy.

    Why is PGT done?

    PGT is done for several reasons:

    1. To increase the chances of pregnancy
      Healthy embryos are more likely to implant and grow.
    2. To reduce the risk of miscarriage
      Some miscarriages are caused by genetic abnormalities in the embryo. PGT helps reduce that risk.
    3. To prevent genetic diseases
      If a parent is a carrier of a known genetic condition (like cystic fibrosis, thalassemia, or Tay-Sachs), PGT can help make sure the embryo doesn’t carry the same condition.
    4. To help older women trying to conceive
      As women age, the chances of chromosomal abnormalities in embryos increase. PGT can help identify the healthiest embryos.

    Types of PGT

    There are three main types:

    1. PGT-A (for Aneuploidy):
      Checks if the embryo has the right number of chromosomes. Too many or too few can lead to problems like Down syndrome or failed implantation.
    2. PGT-M (for Monogenic disorders):
      Used when parents have or carry a known single-gene disorder. It checks if the embryo inherited the faulty gene.
    3. PGT-SR (for Structural Rearrangements):
      Checks for structural issues in the chromosomes, like translocations, which can affect embryo development.

    How is PGT done?

    Here’s a step-by-step of how PGT fits into the IVF process:

    1. IVF is done: Eggs are collected and fertilized with sperm to create embryos.
    2. Embryos grow for about 5 days in the lab.
    3. A small number of cells are gently taken from each embryo (this is called a biopsy).
    4. The cells are tested in a genetic lab.
    5. Healthy embryos are selected based on the test results and are transferred to the uterus.

    Is PGT right for everyone?

    Not everyone doing IVF needs PGT. It’s especially useful for:

    • Couples with a history of genetic disorders
    • Women over 35
    • Couples who’ve had multiple failed IVF attempts or miscarriages
    • People who want to reduce the risk of passing on inherited conditions

    Your doctor or fertility specialist can help decide if it’s the right choice for you.

    Preimplantation Genetic Testing doesn’t guarantee a pregnancy, but it can greatly improve your chances of success and reduce heartbreak. It’s a powerful option in modern fertility care — helping hopeful parents take a step closer to building their family.

    If you’re considering IVF and wondering if PGT is something you should explore, talk to your fertility doctor. To book an appointment, call 9849161421 or visit us at MHRT Hospitals for one-one-guidance based on your personal and medical history.